7-Azidoheptanoic acid Methyl ester
7-Azidoheptanoic acid methyl ester
CAS: 1037510-76-1
Molecular Formula: C8H15N3O2
7-Azidoheptanoic acid Methyl ester - Names and Identifiers
| Name | 7-Azidoheptanoic acid methyl ester |
| Synonyms | methyl 7-azidoheptanoate 7-Azidoheptanoic acid Methyl ester 7-Azidoheptanoic acid methyl ester |
| CAS | 1037510-76-1 |
7-Azidoheptanoic acid Methyl ester - Physico-chemical Properties
| Molecular Formula | C8H15N3O2 |
| Molar Mass | 185.23 |
7-Azidoheptanoic acid Methyl ester - Introduction
7-Azidoheptanoic acid methyl ester (methyl 7-azidoheptanoate) is an organic compound with the chemical formula C8H15N3O2.
Nature:
7-Azidopeptanoic acid methyl ester is a colorless liquid with a pungent odor. It has a lower boiling point and melting point. Soluble in many organic solvents at room temperature, such as ethanol, dichloromethane and chloroform.
Use:
7-Azidopeptanoic acid methyl ester is commonly used as a reaction reagent in organic synthesis. It is widely used in "click chemistry" reactions, especially in the construction of molecular and polymer linkages. This reaction can form a stable trifluoromethyl isooxane (TAM) functional group, which can be used in the synthesis of drugs, polymer materials and surface modification.
Preparation Method:
The preparation method of 7-Azidopeptanoic acid methyl ester is usually obtained by a two-step reaction. First, 7-chloroheptanoic acid methyl ester is reacted with triethylamine to obtain 7-chloroheptanoic acid triethylamine salt. The triethylamine salt of 7-chloroheptanoic acid is then reacted with nitrochloride to give methyl 7-azidoheptanoate.
Safety Information:
7-Azidopeptanoic acid methyl ester is an organic compound and should be handled with care. It is irritating and can cause irritation to the eyes, skin and respiratory system. When in use, wear appropriate protective equipment and ensure that you operate in a well-ventilated area. When handling or handling the compound, follow safe operating procedures and avoid incompatible reactions with other chemicals.
Nature:
7-Azidopeptanoic acid methyl ester is a colorless liquid with a pungent odor. It has a lower boiling point and melting point. Soluble in many organic solvents at room temperature, such as ethanol, dichloromethane and chloroform.
Use:
7-Azidopeptanoic acid methyl ester is commonly used as a reaction reagent in organic synthesis. It is widely used in "click chemistry" reactions, especially in the construction of molecular and polymer linkages. This reaction can form a stable trifluoromethyl isooxane (TAM) functional group, which can be used in the synthesis of drugs, polymer materials and surface modification.
Preparation Method:
The preparation method of 7-Azidopeptanoic acid methyl ester is usually obtained by a two-step reaction. First, 7-chloroheptanoic acid methyl ester is reacted with triethylamine to obtain 7-chloroheptanoic acid triethylamine salt. The triethylamine salt of 7-chloroheptanoic acid is then reacted with nitrochloride to give methyl 7-azidoheptanoate.
Safety Information:
7-Azidopeptanoic acid methyl ester is an organic compound and should be handled with care. It is irritating and can cause irritation to the eyes, skin and respiratory system. When in use, wear appropriate protective equipment and ensure that you operate in a well-ventilated area. When handling or handling the compound, follow safe operating procedures and avoid incompatible reactions with other chemicals.
Last Update：2024-04-09 21:01:54
